WebBackground Aldehyde dehydrogenase-2 (ALDH2), a mitochondrial enzyme, detoxifies reactive aldehydes such as 4-hydroxy-2-nonenal (4HNE). A highly prevalent E487K mutation in ALDH2 (ALDH2*2) in East Asian people with intrinsic low ALDH2 activity is implicated in diabetic complications. 4HNE-induced cardiomyocyte dysfunction was … WebAnti-4-Hydroxynonenal Antibody detects level of 4-Hydroxynonenal & has been published & validated for use in ELISA & WB. Anti-4-Hydroxynonenal Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS.

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4-Hydroxynonenal, or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C9H16O2), is an α,β-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. 4-HNE is the primary α,β-unsaturated hydroxyalkenal formed in this process. It is a colorless oil. It is found throughout animal tissues, and in higher quantities … See more 4-Hydroxynonenal is generated in the oxidation of lipids containing polyunsaturated omega-6 acyl groups, such as arachidonic or linoleic groups, and of the corresponding fatty acids viz., the hydroperoxy … See more These compounds can be produced in cells and tissues of living organisms or in foods during processing or storage, and from these latter can be absorbed through the diet. Since 1991, OαβUAs are receiving a great deal of attention because they are being considered … See more • [1] - A biology group devoted to research centered around 4-hydroxynonenal See more 4-HNE has two reactive groups: the conjugated aldehyde and the C=C double-bond, and the hydroxy group at carbon 4. The See more GS-HNE is a potent inhibitor of the activity of glutathione S-transferase, and therefore must be shuttled out of the cell to allow conjugation to … See more WebOct 23, 2024 · To investigate the role of 4HNE in vivo, athymic nude female mice were injected subcutaneously with HT-1080 cells for 7 days and then given intratumoral treatment with 4HNE (5 mg/kg, once every ... sheriff riverside county jobs

4-Hydroxynonenal - Wikipedia

Web常规说明. The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing. Web常规说明. The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of … Web4-Hydroxynonenal Antibodies. Antibodies that detect 4-Hydroxynonenal can be used in several scientific applications, including ELISA, Western Blot, Immunocytochemistry and Immunohistochemistry. Our 4-Hydroxynonenal monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the 4-Hydroxynonenal antibody that fits your needs. spyspot gps.com login