WebThis CDK1 Primary Antibody is cited in 1 publication(s). CDK1 antibody (ABIN1842560). Validated for IHC. Tested in Human, Rat. Order online. English +1 877 302 8632; Contact; Login Comparison List Basket Phone: +1 877 302 8632 Fax: +1 888 205 9894 (Toll-free) E-Mail: [email protected] ...
Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in
WebMay 1, 2024 · The interaction between endogenous CDK1 and AKT1 was confirmed with co-IP with anti-CDK1 antibody and anti-AKT antibody, respectively . When GIST cells were treated with CDK1 inhibitor RO-3306, co-IP of CDK1 with AKT1 (detection of AKT with CDK1 IP) was decreased in GIST430/654 and GIST-T1 cell lines ( Fig. 4D , left). WebFeb 21, 2012 · Cdk1 Liv−/− livers regenerated the lost mass within 3 wk, comparable to controls. (D) To confirm Cdk1 knockout, Western blots with Cdk1 antibodies were performed at different times after PH in control and Cdk1 Liv−/− liver extracts. Cdk1 expression detected in knockout livers is due to liver cells other than hepatocytes. mey emotion top
An overview of Cdk1-controlled targets and processes
WebThe kinase activity of CDK1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of CDK1 also play important regulatory roles in cell cycle control. Destruction of cyclin B during metaphase results in inactivation of CDK1, allowing mitotic exit and cell division. WebCdk1, also known as p34 [cdc2], is a ubiquitously expressed serine/threonine protein kinase. Cdk1/cdc2 has been identified as the catalytic subunit of the maturation-promoting factor (MPF), while cyclin B acts as the regulatory subunit. The binding of these two subunits is critical to the transition into M-phase of the mammalian cell cycle, and this factor's role … WebCDK1 Rabbit Monoclonal Antibody. Cdk1 is a small protein (approximately 34 kilodaltons), and is highly conserved. Cdk1 is comprised mostly by the bare protein kinase motif, which other protein kinases share. Cdk1, like other kinases, contains a cleft in which ATP fits. When bound to its cyclin partners, Cdk1 phosphorylation leads to cell cycle ... mey emotion reduziert