Circshoc2
WebDec 1, 2024 · Studies have investigated the neuroprotective effect and mechanisms of circSHOC2 in ischemic preconditioned astrocyte-derived exosomes (IPAS-EXOs) in cerebral ischemia. When astrocytes were deprived of glucose and oxygen for 6 h, circSHOC2 was significantly up-regulated in the exosomes derived from the ischemic … WebA Subcellular distribution analysis showed the predominant location of circSHOC2 in cytoplasm of HUVECs. U1 acted as the nucleus control, and GAPDH acted as cytoplasm …
Circshoc2
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WebCircular RNA circSHOC2 (hsa_circ_0092670) is located at chromosome 10, whose genomic length is 13,454, with abundant expression in the cerebellum, occipital lobe, frontal cortex, and parietal lobe. A recent study from Chen’s team declared that circular RNA circSHOC2 in ischemic-preconditioned astrocyte-derived exosomes (IPAS-EXOs) could ... Web(E) The size of exosomes was assessed by Nano-ZS analysis. (F) Expression levels of exosomal markers (CD9, TSG101, CD63, and Alix) were measured by western blotting. - "Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis"
WebAug 12, 2024 · CircSHOC2 Knockdown Alleviates High Glucose-Induced Vascular Endothelial Cell Pyroptosis via Targeting miR-145/FOXO1 Axis In Vitro Condition. 1 … WebOverexpression of circSHOC2 in neurons yielded the same protective effects as those from IPAS-EXOs in vitro, and similar results were also observed in the middle cerebral artery …
WebCirc_0006768 down-expressed in ischemic stroke plasma and OGD/R-induced HBMECs and circ_0006768 overexpression partially abolishes the effects Fig. 4 CircSHOC2/miR-145 regulated FOXO1 in high ... WebApr 1, 2024 · CircSHOC2 significantly upregulated: CircSHOC2/miR-7670-3p/SIRT1 axis: Circshoc2 inhibits neuronal apoptosis and alleviates neuronal damage: Chen W et al. Common RNA-SEQ data of human IS focus tissues and controls: hsa-Circ 0078299 and FXN — Neuroprotection and brain recovery: Silva P W et al. There were 170 AIS …
WebSep 25, 2024 · circSHOC2 Acts as a Molecular Sponge for miR-7670-3p in Neurons It has been reported that exosmic circRNAs consistently localized in the cytoplasm, and it is …
WebDiseases: EV Sources: Specific substrates: Modification methods: Modified EVs: Biological effects: Ref. SCI: BMSC: miR-26a: Cell transfection: miR-26a-EV: Axonal ... billy the kid mythsbilly the kid on televisionWebmore, circSHOC2 was found to sponge miR-7670-3p, which regulated SIRT1 expression. Transfection with an miR-7670-3p small interfering RNA (siRNA) (siRNA-7670-3p) and incu- billy the kid newWebSep 26, 2024 · Overexpression of circSHOC2 in neurons yielded the same protective effects as those from IPAS-EXOs in vitro, and similar results were also observed in the … cynthia frelund week 11 picksWebOct 13, 2009 · Cosmic Crush 2. Guide your space rock through the universe and devour all the space junk... one of my favorite games on this site. definetly a must play! It's really … billy the kid outlaw gang websiteWebMar 22, 2024 · Interestingly, in another study conducted by Chen et al. (2024c) they found that circSHOC2 inhibited OGD-induced neuronal apoptosis by promoting autophagy in ischemic brain injury, suggesting a protective role of circSHOC2 and autophagy in ischemic stroke. The discrepancies may be due to the different circRNAs and cell types used in … billy the kid online latinoWebOct 18, 2024 · CircSHOC2 (circ_0092670) is transcribed from the SHOC2 gene and shows significantly increased expression in ischemic preconditioning astrocyte exosomes (IPAS-EXOs). SHOC2 is a prototypical leucine-rich repeat protein that promotes downstream receptor tyrosine kinase (RTK)/RAS signaling and plays important roles in several … billy the kid on amazon season 2