WebThe toxic metabolite of ethylene glycol is oxalic acid, which binds to calcium, resulting in formation of calcium oxalate crystals in the proximal renal tubules. Treatment requires … WebSep 1, 2002 · Ethylene glycol is a solvent found in products ranging from antifreeze fluid and de-icing solutions to carpet and fabric cleaners. 3, 4 According to results from animal …
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WebEthylene Glycol 107-21-1 ... Urinalysis for oxalic acid, an ethylene glycol metabolite, may be useful in diagnosis of poisoning by oral exposure. (3) Health Hazard Information Acute Effects: Acute exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health WebFeb 27, 2024 · The mechanism of toxicity of ethylene glycol involves metabolism, but unlike previous examples this does not involve metabolic activation to a reactive metabolite. Thus, ethylene glycol is metabolized … rounds heating and air
Mono Ethylene Glycol （MEG） CAS NO.: 107-21-1 - News
WebApr 21, 2024 · Firstly, ethylene glycol will be oxidised to oxalic acid. But oxalic acid can still be oxidised. In fact, it is the concept of titration of oxalates with potassium … WebEthylene glycol can cause both renal and developmental toxicity, with metabolism playing a key role in the mode of action (MOA) for each form of toxicity. Renal toxicity is ascribed to the terminal metabolite oxalic acid, which precipitates in the kidney in the form of calcium oxalate crystals and i … WebAug 1, 2011 · During metabolism, ethylene glycol breaks down to glycolic acid and then to oxalic acid by the action of alcohol dehydrogenase. Oxalate binds calcium, leading to calcium oxalate crystals, which are deposited in many tissues but are most readily detected in … strawberry glazed donut calories