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Phospho eif4b

WebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP … WebJan 5, 2024 · The translation initiation factor eIF4A is a member of the “DEAD box” family of helicases that catalyze the ATP-dependent unwinding of RNA duplexes and facilitates 43S ribosome complex scanning through highly structured regions of the 5′-untranslated region (UTR) and recognition of the AUG initiation codon.

大鼠热休克蛋白β6(HSPβ6)检测试剂盒_价格_上海酶联生物科技有 …

WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors … WebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy. phil leaf space https://ladysrock.com

Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) - Abcam

WebEIF4B Antibody (phospho-Ser422) LS-C826726 Antibody: EIF4B Rabbit anti-Human Polyclonal (pSer422) Antibody . Reactivity: Mouse, Rat, Human . Applications: ELISA, IF, IHC, WB . Format: Unconjugated . Price: 1 mg/$357. Select. EIF4B Antibody LS-C334046 Antibody: EIF4B Rabbit anti-Human Polyclonal Antibody ... WebOct 6, 2008 · Insulin stimulation resulted in phosphorylation of eIF4B as detected by both the phospho-eIF4B Ser422 antibody as well as the phospho-PKB substrate antibody (Figure 5a, lanes 1 and 2). phillding

eIF4B phosphorylation at Ser504 links synaptic activity …

Category:The mTOR/PI3K and MAPK pathways converge on eIF4B to …

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Phospho eif4b

大鼠热休克蛋白β6(HSPβ6)检测试剂盒_价格_上海酶联生物科技有 …

WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins … WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.

Phospho eif4b

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WebRecombinant Anti-eIF4B (phospho S406) antibody [EPR7683] - BSA and Azide free (ab248698) Datasheet Certificate of Compliance Submit a review Submit a question Product price, shipping and contact information Currently … WebeIF4B (eukaryotic translation initiation factor 4B), an RNA binding protein, is essential for the binding of mRNA to the 43S pre-initiation complex, which consists of the 40S ribosomal …

WebJun 8, 2024 · The phosphorylation of eIF2α occurs on serine 51 in response to the activation of one out of four eIF2α kinases 4, 5, 6. EIF2AK1, commonly known as heme-regulated inhibitor (HRI), is activated by... WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react …

WebJun 8, 2006 · eIF4B Ser422 phosphorylation persists in cells lacking S6K1 and S6K2 To further corroborate the existence of an eIF4B kinase that is distinct from S6K in cells … WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using …

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WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and … phil leadbetter dobroWebPhospho-EIF4B-S422 Rabbit pAb (AP0775) Datasheet SDS Tested applications: WB Reactivity: Human Western blot analysis of extracts of HeLa cells, using Phospho-EIF4B-S422 antibody (AP0775) at 1:2000 dilution. HeLa cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight. trying on baby diapers twitterWebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using phospho-EIF4B-S422 antibody (AP0278). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. phil leakeWebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … phil leakeyWebNov 18, 2016 · The activity of eIF4B is modulated by phosphorylation, which is mediated by two major signaling pathways, the MEK1/2-ERK1/2-RSK pathway and the PI3K-Akt-mTORC1-S6K pathway [8], [9], [11], [12]. Overexpression or depletion of eIF4B affects cell survival and proliferation [13], [14]. phil learney performanceWebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP Lysates/proteins at 10 µg per lane. Secondary All lanes : goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 69 kDa Observed band size: 69 kDa phil learney academyWebInvitrogen Anti-Phospho-EIF4B (Ser504) Polyclonal, Catalog # PA5-114571. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (PFA fixed) … phil leary