Small ubiquitin-related modifier 2
WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ... WebSmall ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm. [ 1] [ 2] Immunogen human SUMO3 fusion protein Application Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and …
Small ubiquitin-related modifier 2
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WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... WebNov 26, 2024 · Small ubiquitin-related modifiers (SUMOs) are a group of proteins known to greatly influence various cellular biological processes, 4 such as the cell cycle, signal transduction, immune recognition, cell apoptosis, cell proliferation and differentiation, protein transport, organ origin, inflammation, Ag presentation, endoplasmic reticulum …
WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ...
WebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the … WebMar 15, 2012 · SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the …
WebMar 21, 2024 · SUMO2 (Small Ubiquitin Like Modifier 2) is a Protein Coding gene. Diseases associated with SUMO2 include Phlyctenulosis . Among its related pathways are Transport of the SLBP independent Mature mRNA and Homology Directed Repair . Gene Ontology (GO) annotations related to this gene include RNA binding and SUMO transferase activity .
WebApr 13, 2024 · Tumor cells are known to produce high amounts of intracellular lipids, leading to increased levels of fatty acids, cholesterol and membrane phospholipids. Death domain-associated protein (DAXX) is a small ubiquitin-related modifier (SUMO)-binding protein that plays a role in transcription regulation by interacting with transcription factors such as … pop up christmas shop wellingtonWebJul 22, 2014 · Small ubiquitin-related modifier (SUMO), one of these UBLs, is an essential PTM in eukaryotic cells that is involved in various cellular functions including gene expression regulation, DNA repair, intracellular transport, and response to viral and bacterial infections ( 1 – 5 ). pop up christmas tree hsnWebOverview Product name Anti-Sumo 2 + Sumo 3 antibody See all Sumo 2 + Sumo 3 primary antibodies Description Rabbit polyclonal to Sumo 2 + Sumo 3 Host species Rabbit Specificity Recognises 2 bands representing Sumo 2 and Sumo 3 at 15 and 18kDa in Hela Nuclear extract by Western blotting. Tested applications pop up christmas shops near mepop up christmas grottoUniProt P61956 · SUMO2_HUMAN Protein Small ubiquitin-related modifier 2 Gene SUMO2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 95 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST … See more This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. 1. Name1 2. See … See more sharon leftwichWebMay 1, 2009 · The present study aimed to produce and pathophysiologically evaluate the metallothionein (MT) fusion protein. A recombinant plasmid containing DNA segment coding the pET-glutathione transferase (GST)-small ubiquitin-related modifier (SUMO)-MT fusion protein was inserted into Escherichia coli for expression. The expression level of … sharon lee wittWebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. pop up christmas cards moma