Two znf-ubp domains in isopeptidase t usp5

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August undefined, 2024

WebApr 12, 2024 · Ubiquitin-specific protease 5 (USP5), also known as isopeptidase T, is a DUB in the USP family. USP5 harbors a catalytic core composed of the Cys- and His-boxes, as … WebApr 4, 2006 · Structure of the ZNF UBP domain from deubiquitinating enzyme isopeptidase T (IsoT) Released: 04 Apr 2006. DOI: 10.2210/pdb2g43/pdb. Source organism: Homo …

Inhibition of the deubiquitinase USP5 leads to c-Maf protein ...

WebThe ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell. 2006; 124: 1197-1208. Abstract; Full Text; Full Text PDF; ... Two ZnF-UBP domains in isopeptidase T (USP5). Biochemistry. 2012; 51: 1188-1198. Crossref; PubMed; Scopus (36) Google Scholar, 30. Falquet L. Paquet N. Frutiger S. Hughes G.J. WebIsopeptidase T (IsoT/USP5) is a deubiquitinating enzyme that is largely responsible for the disassembly of unanchored polyubiquitin in the cell. IsoT has four ubiquitin binding … sec ruling on xrp

Deubiquitylases USP5 and USP13 are recruited to and

WebDec 1, 2024 · Non-UBP domains Function Reference; 1: UBP1 (AT2G32780) Zf-UBP: canavanine resistance: Yan et al. (2000) UBP2 (AT1G04860) Zf-UBP: ... Two ZnF-UBP domains in isopeptidase T (USP5) Biochemistry, 51 (2012), pp. 1188-1198. CrossRef View in Scopus Google Scholar. Bender and Snedden, 2013. WebJan 31, 2024 · Wilkinson KD et al. (2012) Two ZnF-UBP domains in. isopeptidase T (USP5). Biochemistry 51, 1188 ... WebThe UBP-type zinc finger domain crystallizes as a dimer linked by a disulfide bond between the Cys-195 residues of both molecules, ... Isopeptidase T; Ubiquitin thioesterase 5; … pure beauty mini pre rolls

Structure?Activity Relationship of USP5 Inhibitors - osti.gov

Structural insights into interactions between ubiquitin specific ...

WebA late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]. Gencode Transcript ... WebHuman Gene USP5 (uc001qri.4) Description: Homo sapiens ubiquitin specific peptidase 5 (isopeptidase T) (USP5), transcript variant 1, mRNA. RefSeq Summary (NM_001098536): Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin … sec rushing leadersWebMar 6, 2006 · All characterized ubiquitin binding domains recognize a hydrophobic patch on ubiquitin containing I44. Here we report the crystal structures of the zinc finger ubiquitin … sec rushing stats

"WebThe ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell. 2006; 124: 1197-1208. Abstract; Full Text; Full Text PDF; ... " - Two znf-ubp domains in isopeptidase t usp5

Inhibition of the deubiquitinase USP5 leads to c-Maf protein ...

Deubiquitylases USP5 and USP13 are recruited to and

Two znf-ubp domains in isopeptidase t usp5

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